hrp0097p1-326 | Growth and Syndromes | ESPE2023

Sex Non-Specific Growth Charts and Potential Clinical Implications in the Care of Transgender Youth and Rare Disease Populations

Bomber Eric , Golob Laura , Miller Bradley , Addo Yaw , Rogol Alan , Jaber Mutaz , Sarafoglou Kyriakie

Background: Although Centers for Disease Control and Prevention (CDC) and World Health Organization growth charts, dichotomizing “girls versus boys,” are commonly used, scenarios exist where this binary approach may not be ideal. These scenarios include care for transgender youth undergoing transitions, non-binary youth, and rare diseases where sex-specific growth chart creation is impractical. There is a need for growth charts and z-score calculat...

hrp0097fc14.1 | Late Breaking | ESPE2023

Sleep health characteristics in children with congenital adrenal hyperplasia

Golob Laura , Liu Wenxi , Mercado-Munoz Yesica , Singh Anvita , Hodges James , Siegel Lianne , Morero Helena , Gao Zan , Simon Stacey , Sarafoglou Kyriakie

Introduction: Cortisol secretion is circadian-driven and plays a significant role in sleep quality. In children with congenital adrenal hyperplasia (CAH) hydrocortisone is the preferred treatment. Hydrocortisone has a short half-life producing alternating hyper- and hypocortisolemia, a non-physiologic cortisol profile, likely disrupting sleep. However, minimal literature exists on sleep health in children with CAH.Objective:</str...